EMBL-EBI ROI 20-26x on £50M/yr (£1B-£1.3B annual user value)

The European Molecular Biology Laboratory - European Bioinformatics Institute operates on approximately £50 million/year and generates an estimated £1 billion to £1.3 billion annually in user value — a return of roughly 20:1 to 26:1 (S-0104).

The measurement uses commissioned economic-impact studies that quantify time savings, methodology improvements, and downstream research enabled by EMBL-EBI's data services. The methodology is conservative: it captures only directly attributable user value, not network effects, capability effects on cross-institutional research, or AI training value.

The figure is the strongest available anchor for biological-data-infrastructure ROI in the European context. It establishes that even at the low end of the documented ROI range, the return is order-of-magnitude positive. The case is one of the empirical inputs to C-0031.