Begley & Ellis 2012 — Amgen replication of cancer biology

Begley, C.G. & Ellis, L.M. "Drug development: Raise standards for preclinical cancer research." Nature 483:531-533, 2012.

Key facts: Amgen attempted to replicate 53 landmark preclinical cancer studies; succeeded on 6 (~11%).

Use: E-0034, C-0022.

Original whitepaper reference: [48]